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Reviews

CRISPR–Cas9 Structures and Mechanisms

 

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Simulations

Cas9-catalyzed DNA Cleavage Generates Staggered Ends: Evidence from Molecular Dynamics Simulations

Probing the structural dynamics of the CRISPR-Cas9 RNA-guided DNA-cleavage system by coarse-grained modeling

Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations

Experiments with structural & mechanistic focus. 

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

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Layman news:

https://www.wired.com/2017/06/crispr-mutations/




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